dna capture and sequencing of exomes Search Results


90
WuXi NextCODE dna exome capture and sequencing
Dna Exome Capture And Sequencing, supplied by WuXi NextCODE, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dna+capture+and+sequencing+of+exomes/dna+exome+capture+and+sequencing/pmc07310025-73-3-15
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dna exome capture and sequencing - by Bioz Stars, 2026-10
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SeqWright dna isolation, exome capture and sequencing
Dna Isolation, Exome Capture And Sequencing, supplied by SeqWright, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dna+capture+and+sequencing+of+exomes/dna+isolation++exome+capture+and+sequencing/pmc05810006-139-5-9
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90
Broad Institute Inc whole exome and whole genome dna sequencing and methylation epic array analyses
Whole Exome And Whole Genome Dna Sequencing And Methylation Epic Array Analyses, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dna+capture+and+sequencing+of+exomes/whole+exome+and+whole+genome+dna+sequencing+and+methylation+epic+array+analyses/pmc08654574-947-2-17
Average 90 stars, based on 1 article reviews
whole exome and whole genome dna sequencing and methylation epic array analyses - by Bioz Stars, 2026-10
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GATC Biotech dna isolation and exome sequencing
Characterisation of ex vivo crizotinib-resistant cell lines. ( A ) Circos plot displaying nonsynonymous somatic mutations and copy number variations in H2228-CR2, -CR4 and -CR6 samples (compared with H2228-CS) that were analysed after <t>exome</t> <t>sequencing.</t> Mutations are displayed as coloured radial lines and those predicted as functional are labelled. The inner ring displays copy number data for each sample. Zoomed chromosome 2 is displayed in the top left section. ( B ) Analysis of ALK signalling pathway by western blot in ex vivo H2228 cell lines (CR=crizotinib resistant; CS=crizotinib sensitive). ( C ) Measure of the basal level of pALK in H2228-CS and -CR cell lines by ELISA.
Dna Isolation And Exome Sequencing, supplied by GATC Biotech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dna+capture+and+sequencing+of+exomes/dna+isolation+and+exome+sequencing/pmc05117788-27-4-9
Average 90 stars, based on 1 article reviews
dna isolation and exome sequencing - by Bioz Stars, 2026-10
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90
Clinomics Inc whole exome sequencing and dna copy analysis
(A) Copy number (Depth ratio) and allelic imbalance (B allele frequency) for chromosome 1 (top) and the entire genome in the largest tumor from patient III:2 were evaluated by whole <t>exome</t> <t>sequencing.</t> While no copy loss for chromosome 1 was observed, the allelic imbalance (B allele frequency) analysis demonstrated a significant loss of allelic variation in most of the qter arm of chromosome 1, including the CDC73 locus, indicating a copy neutral LOH event. (B) Copy number analysis was confirmed using quantitative PCR of selected exons (1, 7, 10, 11, 14 and 17) spread throughout the length of the CDC73 gene. The gene structure for CDC73 and location of the primers is indicated. Copy number was normalized to blood DNA from patient III:2 and a normal copy number pattern was observed in both tumors from patient III:2.
Whole Exome Sequencing And Dna Copy Analysis, supplied by Clinomics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dna+capture+and+sequencing+of+exomes/whole+exome+sequencing+and+dna+copy+analysis/pmc06382532-76-18-28
Average 90 stars, based on 1 article reviews
whole exome sequencing and dna copy analysis - by Bioz Stars, 2026-10
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Image Search Results


Characterisation of ex vivo crizotinib-resistant cell lines. ( A ) Circos plot displaying nonsynonymous somatic mutations and copy number variations in H2228-CR2, -CR4 and -CR6 samples (compared with H2228-CS) that were analysed after exome sequencing. Mutations are displayed as coloured radial lines and those predicted as functional are labelled. The inner ring displays copy number data for each sample. Zoomed chromosome 2 is displayed in the top left section. ( B ) Analysis of ALK signalling pathway by western blot in ex vivo H2228 cell lines (CR=crizotinib resistant; CS=crizotinib sensitive). ( C ) Measure of the basal level of pALK in H2228-CS and -CR cell lines by ELISA.

Journal: British Journal of Cancer

Article Title: Emergence of resistance to tyrosine kinase inhibitors in non-small-cell lung cancer can be delayed by an upfront combination with the HSP90 inhibitor onalespib

doi: 10.1038/bjc.2016.294

Figure Lengend Snippet: Characterisation of ex vivo crizotinib-resistant cell lines. ( A ) Circos plot displaying nonsynonymous somatic mutations and copy number variations in H2228-CR2, -CR4 and -CR6 samples (compared with H2228-CS) that were analysed after exome sequencing. Mutations are displayed as coloured radial lines and those predicted as functional are labelled. The inner ring displays copy number data for each sample. Zoomed chromosome 2 is displayed in the top left section. ( B ) Analysis of ALK signalling pathway by western blot in ex vivo H2228 cell lines (CR=crizotinib resistant; CS=crizotinib sensitive). ( C ) Measure of the basal level of pALK in H2228-CS and -CR cell lines by ELISA.

Article Snippet: The DNA isolation and exome sequencing were performed by GATC Biotech ( https://www.gatc-biotech.com/en/index.html ) according to their guidelines.

Techniques: Ex Vivo, Sequencing, Functional Assay, Western Blot, Enzyme-linked Immunosorbent Assay

(A) Copy number (Depth ratio) and allelic imbalance (B allele frequency) for chromosome 1 (top) and the entire genome in the largest tumor from patient III:2 were evaluated by whole exome sequencing. While no copy loss for chromosome 1 was observed, the allelic imbalance (B allele frequency) analysis demonstrated a significant loss of allelic variation in most of the qter arm of chromosome 1, including the CDC73 locus, indicating a copy neutral LOH event. (B) Copy number analysis was confirmed using quantitative PCR of selected exons (1, 7, 10, 11, 14 and 17) spread throughout the length of the CDC73 gene. The gene structure for CDC73 and location of the primers is indicated. Copy number was normalized to blood DNA from patient III:2 and a normal copy number pattern was observed in both tumors from patient III:2.

Journal: Urology

Article Title: CDC73 germline mutation in a family with mixed epithelial and stromal tumors

doi: 10.1016/j.urology.2018.11.013

Figure Lengend Snippet: (A) Copy number (Depth ratio) and allelic imbalance (B allele frequency) for chromosome 1 (top) and the entire genome in the largest tumor from patient III:2 were evaluated by whole exome sequencing. While no copy loss for chromosome 1 was observed, the allelic imbalance (B allele frequency) analysis demonstrated a significant loss of allelic variation in most of the qter arm of chromosome 1, including the CDC73 locus, indicating a copy neutral LOH event. (B) Copy number analysis was confirmed using quantitative PCR of selected exons (1, 7, 10, 11, 14 and 17) spread throughout the length of the CDC73 gene. The gene structure for CDC73 and location of the primers is indicated. Copy number was normalized to blood DNA from patient III:2 and a normal copy number pattern was observed in both tumors from patient III:2.

Article Snippet: ClinOmics Analysis: DNAs from a tumor and matched normal kidney tissue from Patient III:2 were subjected to whole exome sequencing and DNA copy analysis as part of a ClinOmics tumor evaluation protocol at the NIH.

Techniques: Sequencing, Real-time Polymerase Chain Reaction